Designing HVAC systems for health care patient and critical environment spaces is dictated by strict environmental and safety standards, and one of the most important components that must be taken into consideration is effective airflow design (EAD). EAD not only helps meet airflow change and industry standards but is critical in limiting the contraction of airborne illnesses and can reap considerable cost savings for facilities. Therefore, when designing for health care facilities, it is important to abide by airflow and air quality standards. This is particularly true for three priority rooms for EADs: hybrid operating rooms, patient rooms, and isolation rooms.