R-453A is a hydrofluo-rocarbon/hydrocarbon (HFC)/(HC) based, non-ozone depleting, low-global warming potential (GWP), direct drop-in replacement refrigerant blend for HCFC-22 (R-22). It can be used to replace R-22 in both air conditioning and refrigeration applications across the temperature ranges where R-22 is commonly used. Refrigeration applications using R-453A can reach down to minus 20°F evaporator temperatures. Applications for R-453A include air conditioning, commercial and industrial refrigeration, chillers, beer cellars, cold storage, refrigerated transport, supermarkets, appliances, dairy chillers, and others.
R-453A is a six-part blend of HFC-125, HFC-32, HFC-134a, HFC-227ea, butane, and isopentane. Butane and isopentane are both pure hydrocarbons (HCs) incorporated into the blend to enhance oil return to the compressor. The blend is listed in the U.S. Environmental Protection Agency’s (EPA’s) Significant New Alternatives Policy (SNAP) program. R-453A has an ASHRAE safety classification of A1, meaning it has low toxicity and is nonflammable.